Sr. Research Associate – Cell Process Development, Process Science

Who We Are:

At Dendreon, we’re transforming the battle against cancer with personalized immunotherapy. Our flagship product, PROVENGE® (sipuleucel-T), was the first FDA-approved immunotherapy for metastatic castrate-resistant prostate cancer, utilizing a patient’s own immune cells to fight the disease.

If you’re driven by the opportunity to make a meaningful impact on cancer patients' lives, we invite you to join our team. With Immunotherapy Manufacturing Facilities in Seal Beach, CA, and Union City, GA, a strong Research & Development group in Seattle, WA, and a highly skilled Commercial team across the nation, Dendreon is at the forefront of cancer treatment innovation.

Core Values:

• Put Patients First: Every day is an opportunity to improve the lives of those living with cancer.
• Act with Integrity: We commit to transparency, honesty, and always doing what’s right.
• Build Trust: Trust is earned through candid, open communication and a collaborative approach.
• Raise the Bar: We embrace continuous improvement and innovation, always striving to elevate our people.
• Drive Results: We are accountable to each other and deliver success together.

Job Summary:

The Sr. Research Associate applies technical knowledge to contribute to the development, optimization, technology transfer and troubleshooting of processes to manufacture cell therapies. The associate in this position will be hands-on in the laboratory and report to the Manager of Process Development. A strong interpersonal and communication skills with a collaborative, team-first mindset is a must

Key Responsibilities:

• Support development developing, validation and troubleshooting autologous and allogenic cellular therapies.
• Utilize various cell culture platforms such as Prodigy, Xuri, G-Rex, Hyperstack, and stirred tank reactor to develop and scale-up clinical cell therapy processes
• Conduct process optimization and characterization studies for cGMP manufacture of cellular therapies.
• Participate in technology transfer and validating new and optimized cell processes.
• Participate in technical support to a manufacturing for process deviations and failures by writing and reviewing technical assessments and participate in investigation teams.
• May act as subject matter expert (SME) on cell process development during non-conformance investigations and regulatory inspections.
• Provide process training to GMP manufacturing operators, when required.
• Maintain study records and document results in technical reports.
• Write or revise, operating procedures, as appropriate.
• Complete appropriate GMP training, when needed.
• Other duties as assigned.

   

   

Scope:

• Uses professional concepts, company policies and procedures to solve a variety of problems.
• Works on problems of moderately complex scope.
• Works with a moderate level of independence on moderately complex tasks.

Job Requirements:

Education:

• BS in Molecular Biology, Biochemistry, or a related field.

Experience:

• 5 years minimum experience in multicolor flow cytometry
• Demonstrated experience working with cell culture bioreactor technologies
• Familiarity working with cross-functional teams in a GMP regulated environment.
• Ability to solve problems through analysis.
• Excellent written and verbal communication skills.
• Strong organizational skills required.

Working Conditions and Physical Requirements:

• On-site based role at our Seattle, WA office (NOT Remote)
• This role operates in a standard office setting using standard office equipment.
• Role requires frequent use of video conferencing, standard office software, and digital collaboration tools.
• Must have the ability to lift 10 – 20 lbs.
• Must have the ability to work in an office environment around laboratories, manufacturing areas and equipment with exposure to blood, blood products or OPIM (other potentially infectious materials) while donning required personal protective materials.